Why Application Allowlisting Is Now Essential for CMMC Compliance

How DoD contractors can simplify security while meeting modern standards

As cyber threats continue to evolve, traditional security tools like antivirus software are no longer enough—especially for organizations in the Department of Defense (DoD) supply chain. The need for a proactive, Zero Trust approach to cybersecurity has never been more urgent. One solution is rapidly gaining traction: application allowlisting.

This blog post explores how allowlisting aligns with the Cybersecurity Maturity Model Certification (CMMC), why it’s now mandated for CMMC Level 2 compliance, and how PC Matic’s solution makes it easier for organizations to meet these rigorous standards.

What Is Application Allowlisting?

Application allowlisting is a security method that blocks all unknown applications by default and allows only those explicitly approved to run. This “default deny” approach drastically reduces the risk of ransomware, malware, and zero-day attacks.

Unlike blacklisting, which reacts to known threats, allowlisting prevents all unauthorized or malicious software from ever executing—even if it’s never been seen before.

Why the Shift? CMMC Level 2 and NIST Say So

With the release of NIST SP 800-171 Rev 3, application allowlisting is now the only approved software execution control method to meet CMMC Level 2’s Practice CM.L2-3.4.8. Previous guidelines permitted either allowlisting or blacklisting. That’s no longer the case.

Allowlisting is also supported by other top-tier government agencies:

  • NIST calls it the “single most effective strategy” against malware.
  • CISA emphasizes its impact on reducing attack surfaces.
  • NSA includes it in its Top 10 Cybersecurity Mitigations.

Overcoming the Challenges of Traditional Allowlisting

Historically, allowlisting was difficult to implement due to manual configurations and constant updates. But modern solutions, like PC Matic, have revolutionized the process through automation and cloud-based allowlist management. This removes much of the complexity and user frustration, making allowlisting viable for organizations of all sizes.

How PC Matic Makes Compliance Simple

PC Matic’s application allowlisting solution is purpose-built to help DoD contractors and Managed Service Providers (MSPs) meet CMMC and NIST requirements.

Key features include:

  • Zero-Trust Enforcement: Blocks all unapproved software by default.
  • Global Allowlist of 22+ Billion Files: Reduces false positives and streamlines deployment.
  • Automated Threat Analysis: Unrecognized files are reviewed by malware experts.
  • Cloud-Based Management: Flexible deployment across diverse environments.
  • Seamless CMMC Alignment: Built to meet CM.L2-3.4.8 and NIST SP 800-171 Rev 3 directly.

Conclusion: Build a Stronger, Compliant Cyber Defense

As the DoD tightens its security expectations, application allowlisting has moved from a “nice-to-have” to a “must-have.” With tools like PC Matic, organizations can move beyond reactive security models and embrace a proactive, Zero Trust approach that protects data, systems, and supply chain integrity.

Want to dive deeper?
Read the full whitepaper: Application Allowlisting and CMMC – Whitepaper

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